The Bills defense a big concern after last week. Little to no pass rush from the big money defensive line, and too many big plays allowed in the secondary.

The Chiefs and quarterback Matt Cassel played well at times in a Week 1 setback against Atlanta, but Cassel also threw two interceptions, and the Bills would love to force KC into more of those mistakes.

"We have to do a great job of getting consistent pressure on him, not allow him to throw on the timing I'm sure he wants," safety George Wilson said. "Make him move the launch point. And then when we get an opportunity to get our hands on some footballs, week make those plays."