It was a spooky moment. Up six, trying to run out the clock, and needing a first down to do so, Ryan Fitpatrick made his biggest mistake of the season. He threw a low pass, behind Donald Jones. Whether it was a bad read or bad communication, it was a trick for Bills and a treat for the Titans.

"I just got greedy in a situation that I did not have any business being greedy in," Fitzpatrick said after the game. "It was a dumb throw, dumb decision by me.

"Third down at the end of the game, game on the line, Chan (Gailey) put the ball in my hands essentially and I threw an interception. So that one hurts."

It was one costly mistake that negated a 27 for 35 performance, with three touchdowns.

"He made a bad throw at the end," Chan Gailey said. "Other than that, he played really, really well. He made one bad throw.

"If you get rid of all of the quarterbacks for one bad throw, you are not going to have any quarterbacks left."

Because of the bye week, the Bills will carry this bitter taste for the next two weeks. While the Fitzpatrick play was the most obvious game-changing moment, George Wilson was upset that he was not able to complete an interception on the Titans final drive.

"I personally feel like it was on me," the safety proclaimed after the game. "I had an opportunity to get an interception and I did not come up with the ball, which would have sealed the victory.

"Those are the plays we need to make in order to be a good football team. I did not make that play and I personally feel like it is on me."

While that was certainly not the turning point of the game, Wilson's comments did draw attention to the fact that the Bills defense had distinct struggles in the game. That unit continued baffling troubles against the run. Chris Johnson put up 195 yards and two touchdowns. He had not found the end zone in his previous 10 games.

"I did not think we would give up as many yards as we have given up," Gailey acknowledged. "We just have to find out exactly what the problems are, and we are not solving them right now. If we do not, we are in for a long year."

Gailey and his staff have two weeks to make the necessary adjustments. At 3-4, the season is not yet slipping away. But things don't get any easier with back to back road games against the Texans and Patriots greeting them in early November.

"I think we have to reevaluate everything you do," the head coach noted. "That is what you do with the bye week. You reevaluate everything."